Image sensor is an important part of the industrial camera. According to difference of the original, it can be divided into CCD and CMOS sensors. In the last 25 years of the last century, CCD technology has been leading the trend of the imaging sensor. It is a high-resolution and high-quality image sensor which can be integrated on a very small chip. However, in recent years, with the rapid development of the semiconductor manufacturing technology, the size of the integrated transistor is becoming smaller and smaller, and the performance is much better. CMOS image sensor obtains rapid development in the recent years, and it seems CMOS image sensor has overtaken CCD image sensor. CMOS provides the performance on a par with CCD in the mid-end and low-end applications, and has a significant advantage in price. With the development of technology, CMOS will also occupy a space in the high-end application field. This paper makes a detailed explanation to the difference between CCD and CMOS image sensors in the industrial camera.